AAV Vector Security Analysis Service
AAV vectors can effectively bind to target cells and express in the nucleus in a low- or non-toxic manner. Most AAV vectors are designed by using the AAV-2 serotype. These AAV-2 vectors can successfully transduce many human tissues, such as liver, lung, and brain. Several novel AAV vector strategies have been developed to improve the safety of AAV vectors. For example, all AAV viral coding sequences have been removed to reduce toxicity and obtain more stable expression levels in specific cells. Gene therapy has made significant progress, and AAV vector-based therapies have shown encouraging results in the treatment of various diseases. Preliminary studies have shown that some AAV vectors can enter host cells to help the replication process, but the expression of AAV genes can cause toxicity in in vivo animal models. Therefore, many techniques have been established in preclinical research to evaluate the safety and toxicity of AAV vectors.
- As an expert in AAV-based gene therapy, CD BioSciences is committed to the comprehensive safety analysis and toxicity assessment of AAV vector services to promote the progress of gene therapy in human diseases.
- CD BioSciences pseudotyping the AAV2 vector genome using capsids from other types of AAV serotypes has been shown to be more effective and safer for gene transfer in the treatment of melanoma.
- In addition, CD BioSciences also provides a set of AAV vector administration detection methods, such as arterial blood gas analysis, inflammatory cytokine analysis, and lung mechanics analysis to test the safety of AAV vectors.
- CD BioSciences has developed a number of in vivo immunogenicity platforms to determine the cellular immune response to model antigens expressed by AAVs.
Our service items
|Project name||AAV vector security analysis service|
|Product delivery mode||We will complete the project on time according to the agreed time, summarize the experimental data and conclusions, and complete the experimental report.|
Why choose us?
CD BioSciences provides corresponding AAV vector security analysis service. AAV vector security analysis service is a personalized and customized innovative scientific research service. Before determining the corresponding analysis plan and price, each project needs to be evaluated. Our experienced and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each adeno-associated virus project. If you want to know more about service prices or technical details, please feel free to contact us.