Specialized Antibody Characterization

Antibody characterization is important in research and biopharmaceutical development. All therapeutic proteins produced by current technology are heterogeneous in the final product, because various modifications occur at different stages of production. Because of these heterogeneities, thorough characterization is necessary to reproducibly and safely produce therapeutic proteins. CD BioSciences can use a variety of techniques to fully identify antibodies. At present, more and more new monoclonal antibody (mAb) drug therapies are entering commercial clinical trials. This trend places strong demands on reliable, fast and effective solutions for mAb characterization.

Overall Solutions

  • Affinity Analysis

CD BioSciences uses a professional platform to determine the kinetic properties of antibody-antigen interactions for test antibodies or antibody fragments as purified or unpurified samples.

  • Epitope Binning

Epitope binning studies the sequential binding of two antibodies to the antigen. Antibodies with similar blocking properties are divided into containers specific for the same or overlapping epitopes. CD BioSciences uses two proven platforms to test the ability of multiple antibodies to block each other's binding to antigens.

  • FcRy and FcRn Binding Assays

For your biotherapeutics development, CD BioSciences uses the BLI platform to establish a standard human Fcγ receptor panel binding assay in a high-throughput format. Measuring the affinity of antibodies to Fcγ receptors is essential for predicting biological and pharmacological outcomes (such as cytotoxicity or half-life).

  • In Silico Immunogenicity Prediction

Our computer simulation immunogenicity prediction service provides a cost-effective initial analysis of the immunogenicity of biological agents for major MHC class II alleles. We use a well-trained artificial neural network ensemble to provide important information for further engineering design and optimization.

Our Advantages

✓ The CD BioSciences team has extensive knowledge and experience in antibodies. We work with many scientists from many pharmaceutical and biotechnology companies and organizations.

✓ CD BioSciences will complete your project efficiently and on time, and meet your requirements.

✓ CD BioSciences has professional after-sales service: a professional after-sales service team has been established to provide customers with efficient, fast, practical and feasible solutions.

Our Service Items

Project name Specialized antibody characterization
Our services

CD BioSciences offers specialized antibody characterization services to meet the specific needs of different customers. We provide you with the following services but not limited to:

  • Affinity Analysis
  • Epitope Binning
  • FcRy and FcRn Binding Assays
  • Sequence Liability Identification
  • In Silico Immunogenicity Prediction
Sample requirements

100μg each of purified antibody 100μg of purified antigen

Product delivery mode

We will complete the project on time according to the agreed time. We provide you with the study report.

Timeline

3 to 4 weeks

Price Inquiry

Why choose us?

CD BioSciences provides professional specialized antibody characterization to meet the needs of regular customers to determine hits on time and on budget. CD BioSciences relies on the world-class technical expertise, we provide customers with the best quality specialized antibody characterization, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.

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