Adenovirus Vector Service
Classifications of Adenovirus Vector
The first-generation adenoviral vector: generally referred to as the first-generation adenoviral vector with the deletion of E1 or E3 gene, this type of vector can cause the body to produce a strong inflammatory response and immune response when it is not purified. It can be used safely, and the expression cycle in vivo can reach 4 weeks.
The second-generation adenoviral vector: The adenoviral vector with E2A or E4 gene deletion is called the second-generation adenoviral vector, which produces weaker immune response. The capacity and safety of the vector have been improved, but the virus packaging is difficult and the virus is released. And the virus titer drops drastically, and its application is quite limited.
The third-generation adenovirus vector: The third-generation vector is missing all (gutless vector) or most of the adenovirus genes (mini Ad), and can only retain the ITR and packaging signal sequence.
CD BioSciences, with the assistance of our professional scientific team, CD BioSciences provides a series of adenovirus vector, including but not limited to:
- Construction of adenovirus vector
CD BioSciences provides various types of adenovirus vectors with different designs and structures for customers to choose from. The packaging capacity and toxicity of the intestinalless are better than adenovirus vectors. After production and purification, the vector is chemically modified with polymers. Here, in CD BioSciences, PEG and pHPMA are used to modify adenoviral vectors to maintain efficient gene transfer and overcome obstacles that limit clinical applications.
- Adenovirus vector characterization service
CD BioSciences has developed a wide range of assays for the identification of adenoviral vectors. With advanced technology and rich experience, CD BioSciences provides our customers with customized solutions and a series of mature adenovirus vector characterization assays, including but not limited to: adenovirus detection with replication ability, adenovirus vector titration, Adenovirus vector virus particle determination, etc.
- Adenovirus vector purification service
Adenovirus is a very popular gene delivery tool with the advantages of simple operation and high safety. Through long-term efforts, the scientific and technical team of CD BioSciences has established an adenovirus-centric technology platform, including vector construction, packaging, detection and purification. We will provide a comprehensive adenovirus vector purification service for your research with the most rigorous attitude.
- Recombinant adenovirus construction service
Recombinant adenovirus vectors have been widely used to deliver foreign genes to a variety of cell types and tissues in vitro and in vivo. They can easily grow to high titers and can effectively transfer genes to dividing and non-dividing cells. As a leading company in this field, CD BioSciences provides the most advanced recombinant adenovirus vector construction services to meet the needs of basic research and preclinical applications.
- CD BioSciences diversified expression cells are available for selection, scientific and reasonable screening system, optimization of the best experimental conditions.
- The success rate of CD BioSciences experiments is as high as 95%. With a stable experimental system and rich experience, it will save you a lot of time and money.
- CD BioSciences from gene synthesis, protein expression and purification, to the subsequent supporting experimental platform.
Our Service Items
|Project name||Adenovirus vector service|
|Product delivery mode||We will complete the project on time according to the agreed time, summarize the experimental data and conclusions, and complete the experimental report.|
Why choose us?
CD BioSciences provides professional adenovirus vector service, which can meet the needs of regular customers for hit identification on time and on budget. CD BioSciences relies on world-class viral vector technology expertise, we provide the highest quality one-stop adenovirus vector related services for gene delivery, including the design and construction of adenovirus vectors according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.