Cell Line Authentication Service
Misidentification and cross-contamination of cell lines are common problems in life science research. In response, various scientific journals and funding agencies are strictly using recognized cell lines for research purposes, and cell line identification must be performed before approval and/or publication.
Short Tandem Repeat Profiling (STR) technology
Short tandem repeats (STR), also known as microsatellite DNA, which are nucleotides widely present in the genomes of prokaryotes and eukaryotes repeat sequence. STR is formed by repeating core sequence (core repeat units) end-to-end multiple times. The core sequence of each STR has the same structure and the length is 2-6bp, but the number of repeat units and the length of the repeat region are different. Therefore, the distribution of STR among different races and different populations is different, which constitutes STR genetic polymorphism. The number of repetitions at a homologous STR site varies from individual to individual, so as with fingerprint recognition, STR site analysis can also identify individuals. By identifying the specific sequence duplication of an individual's genome at a specific site, its genetic profile can be created. Based on this, the STR analysis method has become an important identification analysis method, which is applied in the fields of forensic medicine, paternity testing and cell identification.
- CD BioSciences uses short tandem repeat analysis (STR) technology to provide comprehensive cell line identification services to ensure that your cells have the correct identity and avoid the risk of misidentification or contamination of cell lines in research.
- In terms of cell STR detection services, CD BioSciences has a team of many returned overseas students. With background advantages and research experience, CD BioSciences provides services for your cell identification and is your partner on the road of scientific research.
- After CD BioSciences obtains the cell genome, we design fluorescently labeled primers for PCR amplification for its polymorphic regions, and then detect the amplified products through the system and software to determine how many repetitive sequences there are at a certain site. At the same time, STR atlas can be drawn, and individuals can be identified by using the atlas.
- Our cell line authentication services are available for human, mouse, rat, and canine cell lines.
Our service items
|Project name||Cell line authentication service|
|Our service feature||
|Product delivery mode||We will complete the project on time according to the agreed time, summarize the experimental data and conclusions, and complete the experimental report.|
Why choose us?
CD BioSciences provides professional cell line authentication service to meet the needs of regular customers to identify hits on time and on budget. CD BioSciences relies on world-class cell engineering technology expertise, we provide customers with the best quality one-stop cell line authentication service, including the development of experimental programs according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.