Yeast Display Service
Yeast display is a new technology that is widely used to express proteins on the surface of yeast after translation and maturation in eukaryotic systems. Therefore, yeast display is superior to phage display for protein or antibody display because the eukaryotic expression environment of yeast cells ensures fine-tuning, such as folding, modification, and translocation before being displayed on the surface. Advantages of yeast display over other in vitro evolution methods include eukaryotic expression and processing, quality control mechanisms of the eukaryotic secretory pathway, minimal avidity effects, and quantitative library screening through fluorescent-activated cell sorting (FACS). Yeast are eukaryotic organisms that allow for complex post-translational modifications to proteins that no other display libraries are able to provide. CD BioSciences provides yeast display technology for yeast display library construction and screening, antibody affinity maturation, etc.
✓ CD BioSciences provides a yeast display platform based on phage and eukaryotes for the in vitro discovery and engineering of effective antibody candidates for therapeutic or diagnostic purposes.
✓ CD BioSciences uses custom-made or licensed state-of-the-art technology libraries to routinely select high-affinity functional antibodies against a wide range of conventional or challenging targets (such as GPCRs).
✓ CD BioSciences can provide a variety of antibody scaffolds (Llama VHH, scFv, Fab, reformatted IgG) upon request.
✓ CD BioSciences has in-depth cooperation with many pharmaceutical companies and research institutes, and has extensive experience in providing them with high-quality products and services.
✓ CD BioSciences specializes in yeast display service and we are committed to contributing to more customers and we can provide all services related to yeast display service in a flexible and comprehensive manner.
Our Service Items
|Project name||Yeast display service|
CD BioSciences offers yeast display service to meet the specific needs of different customers.
✓ The yeast display system uses FACS sorting technology to screen based on antibody affinity and display level, thus eliminating the deviation caused by expression, and can distinguish clones with small differences in affinity.
✓ Yeast display is a multivalent display, which can directly sort high, medium & low affinity clones through sorting at one time, which is very convenient
✓ The antibody screening speed is fast, 100,000 cells can be sorted in 3 minutes, and 100+ unique sequence candidate clones can be obtained.
✓ The affinity and stability of antibodies can be optimized under the same display system.
|Product delivery mode||
We will complete the project on time according to the agreed time.
Why choose us?
CD BioSciences provides professional yeast display service to meet the needs of regular customers to determine hits on time and on budget. CD BioSciences relies on the world-class technical expertise, we provide customers with the best quality yeast display service, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.